ناظمی طرقبهی, زهره (2017) بررسی تأثیر سینبیوتیکهای موجود در ایران بر درمان اسهال حاد در کودکان 6 ماهه تا 5 ساله مراجعه کننده سرپایی به کلینیک. Doctoral thesis, علوم پزشکی سبزوار.
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Abstract
A survey on efficacy of available synbiotics in Iran in the treatment of acute diarrhea in 6 months to 5 years old outpatients Background: Acute diarrhea is a great public health problem. Diarrhea is a leading cause of death in children under five years of age globally with an estimated 1.5 million child deaths per year. Acute diarrhea defined as more than three loose or watery stools in 24 hours lasting not longer than 14 days.primary treatment of diarrhea is replacing of fluid and electrolyte with oral rehydration. Probiotics are traditionally defined as viable microorganisms that have a beneficial effect in the prevention and treatment of specific pathologic conditions when they are ingested. The aim of this study is surveying on available synbiotic (prebiotic plus probiotic) in Iran in the treatment of acute diarrhea. Because of extensive cost of synbiotic surveying on usefulness or uselessness of these products can be effectiveness on decrease of treatment’s cost for family and health system. Materials and Methods: This is a randomized double blind clinical trial.100 patient with acute diarrhea divided to two group of 6 months to 24 months and 24 months to 60 months.Each group devided to two subgroup and randomly assigned to receive specific synbiotic for their age.25 people who has 6 months to 24 months old,receive pedilact(10 drops per day for 5 day) and 25 people who has more than 24 months old recive kidilact (1 suchet per day for 5 day).Then duration of diarrhea lasting is noted and compared.Data was analysed with SPSS. Result: Difference in the mean of duration between two group was not significant (P=0.736 in 6 months to 24 months and P=0.920 in more than 24 months). The mean of duration was 4.02 in interventional group and 3.92 in control which shows the synbiotics were not effictiveness in acute diarrhea. Conclusion: Use of available synbiotic in Iran has no significant advantage vs absolute oral rehydarion therapy and just can increase the cost of treatment. Key Words: Probiotic, Prebiotic, Acute diarrhea
| Item Type: | Thesis (Doctoral) |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | Saeed Shoja |
| Date Deposited: | 16 May 2018 06:40 |
| Last Modified: | 16 May 2018 06:40 |
| URI: | http://eprints.medsab.ac.ir/id/eprint/439 |
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