The effect of Nandrolon Injection with or without obligatory swimming exercise on General changes And Abnormal function of Physiological changes of kidney in rates

ahmadi, shima and tofighi, asghar and seyedi, seyede masoumeh and shirpoor, alireza (2018) The effect of Nandrolon Injection with or without obligatory swimming exercise on General changes And Abnormal function of Physiological changes of kidney in rates. Journal of Sabzevar University of Medical Sciences, 25 (2). pp. 321-329.

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Abstract

Background and Objective: Abuse of anabolic steroids to increase concerns about the harmful effects of these drugs on different organs, including the kidneys has increased. Sports activities such as swimming does not modify the effects of anabolic steroids. In this study, the effects of anabolic steroids with or without swimming the public and biochemical changes in renal tissue of rats was performed.Materials and Methods: The study sample consisted of 32 male rats Wistar, with an average weight of 20 ± 220 g in the form of four groups of nandrolone alone 10 mg / kg (n = 8), nandrolone and forced swim 10 mg / gr (n = 8), forced swim alone (n = 8) and controls (n = 8) were divided. In this study, urine samples were collected to measure biochemical variables. : Data obtained with the software spss version 21 Test and one-way ANOVA significant level P�0 / 05 was performed.Results: H & E and PAS staining nandrolone decanoate + exercise groups compared with control groups and sports inflammation of the glomeruli, tubular atrophy, the number of leukocytes was more evident.Conclusion: The results of swimming exercise any impact on different parts of the kidney of male rats does not allow the use of nandrolone could be change in these sectors.Keywords: nandrolone, sports, swimming, stained H & E, coloring PAS, rats, creatinine, urea

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: Saeed Shoja
Date Deposited: 10 Sep 2018 09:10
Last Modified: 10 Sep 2018 09:10
URI: http://eprints.medsab.ac.ir/id/eprint/686

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