The Effects of high-intensity interval training on chronic inflammation of Lung Tissue in healthy rats

yadegari, mehdi and Mirdar Harijani, Shadmehr and Hamidiyan, GholamReza and Ebrahimi, Maryam (2017) The Effects of high-intensity interval training on chronic inflammation of Lung Tissue in healthy rats. Journal of Biomedicine and Health, 2 (3). pp. 1-9.

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Abstract

Background and Aims: Exercise training with various intensities, has different effects on the immune system response. This study investigated the effect of a period of high intensity interval training on Inflammation markers of lung tissue in healthy Wistar rats.Methods::Twelve male Wistar rats were randomly divided into exercised (n=6) and control groups (n=6). The high intensity interval training program was carried out for 9 weeks. Training program was started with 25 m/min and ended with 70 m/min speed at the final stage. In lung tissue, expression of IL-17 was studied by the Immunohisto-chemistry, and structural changes such as macrophage population, BALT, interstitial tissue and alveolar space volume were measured by stereological assessments. independent T-test was used. P � 0.05 was considered statistically significantResults:The results showed that after the 9 weeks of high intensity interval training, the protein IL-17, macrophage population, BALT volume and interstitial space volume were increased significantly and alveolar space was significantly decreased.Conclusions: It seems that 9 weeks of high intensity interval training program, induced chronic inflammation of the lung and defective remodeling of tissue.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: Saeed Shoja
Date Deposited: 18 Feb 2018 09:39
Last Modified: 18 Feb 2018 09:39
URI: http://eprints.medsab.ac.ir/id/eprint/54

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