Effect of the phenytoin cream on episiotomy healing and pain reduction

Azimi Souteh, Samane (2017) Effect of the phenytoin cream on episiotomy healing and pain reduction. Doctoral thesis, Sabzevar University of Medical Sciences.

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Abstract

Effect of the phenytoin cream on episiotomy healing and pain reduction Abstract Introduction: Episiotomy is one of the most common surgery interventions to facilitate the process of delivery. Phenytoin is known as a cream with antibacterial and anti-inflammation effects as well as it has accelerates effects of tissue. This study aimed to determine the role of phenytoin cream on wound healing in pregnant women underwent episiotomy surgery. Methods and Materials: This was a double-blind clinical trial included 90 women in the age range of 18-35, who were referred to Shahidan Mobini Sabsevar Center, Sabzever, Iran in 2016. Subjects were randomly selected and divided into two Phenytoin and control groups (45 for each). After delivery all of the patients used this creams daily. Recovery assessment was conducted on the tenth and twentieth day by REEDA and VAS scales. Data were analyzed by U-mann Whitney test and Wilcoxon tests using SPSS version 22. Results: The mean of REEDA score on the 10th day after delivery was 5.38 ± 1.78 in the intervention group and 4.41 ± 2.21 in the control group. Comparison of REEDA score on the 10th day after delivery between two groups showed that there was a significant difference between them (Z = -0.01) (P = 0.003). Also, the mean of VAS score on the 10th day after delivery was 5.17 ± 1.48 in the intervention group and was 4.7 ± 1.14 in the control group. Comparison of VAS score on the 10th day after delivery between two groups showed that there was a significant difference between them (Z = 3.43) (P = 0.001) Conclusion: Findings showed that use of topical phenytoin increases rapidity of Episiotomy wound healing. It is recommended to accelerate wound healing of Episiotomy on women. Keywords: Episiotomy, phenytoin, pregnancy, wound healing

Item Type: Thesis (Doctoral)
Uncontrolled Keywords: Episiotomy, phenytoin, pregnancy, wound healing
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Saeed Shoja
Date Deposited: 15 May 2018 06:35
Last Modified: 14 Jan 2019 06:29
URI: http://eprints.medsab.ac.ir/id/eprint/404

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