Ameli, Zahra (2016) The effects of bilineaster drop on the neonatal hyperbilirubinemia. Masters thesis, Sabzevar University of Medical Sciences and Health Services.
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Abstract
Effect of bilineaster drop on the neonatal hyperbilirubinemia Introduction: Hyperbilirubinemia is considered one of the most prevalent problems in newborns. Phototherapy, exchange transfusion, and herbal medicine are common therapeutic approaches for preventing any neurologic damage in infants with neonatal jaundice. However, herbal medicine is less commonly used. Aim:This research aimed to investigate the effect of bilineaster drop on neonatal hyperbilirubinemia. Method: This study was a randomized clinical trial conducted on 98 term neonates (aged 2-14 days) with neonatal jaundice admitted to Ghaem Hospital of Mashhad, Iran, during 2015. These newborns were randomly assigned into intervention (phototherapy and bilineaster drop) and control (only phototherapy) groups. Total and direct serum bilirubin levels were measured at the time of admission and then 12, 24, 36, and 48 h after treatment. Data were analyzed using independent t-test and repeated measures ANOVA through Stata software (Version 12). Findings: Analysis of data showed that both types of bilirubin reduction in hours12 and 24 in the intervention group had significantly (p<0.001) than the control group. But, in hours36 (p=0.06) and 48(p=0.22) were not statistically significantly different (p<0.001) in the between groups. The average time of hospitalization (p<0.001) and readmission rate (p<0.001) in the intervention group was significantly lower than the control group. Repeated measures analysis of variance showed that intervention were not reduce significantly the amount of total (p=0.10) and indirect (p=0.07) bilirubin in both groups. But the main effects analyzes showed that both types of bilirubin reduction had significantly (p<0.001) in both groups. Conclusion: The results of this study demonstrated that the use of bilineaster drop along with phototherapy could cause a significant decrease in the levels of total and direct bilirubin; however, the intervention had no effect on the downward trend of bilirubin. Keywords: Hyperbilirubinemia, Neonatal, Phototherapy, Bilineaster drop
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Hyperbilirubinemia, Neonatal, Phototherapy, Bilineaster drop |
| Subjects: | R Medicine > RT Nursing |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | Saeed Shoja |
| Date Deposited: | 15 May 2018 05:50 |
| Last Modified: | 22 Jan 2019 08:36 |
| URI: | http://eprints.medsab.ac.ir/id/eprint/400 |
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