Ekrami Toroghi, Mehran (2017) Bacterial Etiology of Urinary Tract Infections and Determining their Antibiotic Resistance in Adults Hospitalized in or Referred to the Vase’ee Hospital in Sabzevar during 2016 and 2017. Doctoral thesis, Sabzevar University of Medical Sciences.
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Abstract
Introduction: Urinary tract infection is the most common infectious diseases and Increasing resistance to antimicrobial agents in bacteria is a major problem around the world in treatment of urinary infections. Empiric treatment of urinary infections depends on predictable levels of the causative agents of this kind of infections and awareness of antibiotic sensitivity pattern. This study was conducted to identify causative agents of urinary tract infection and to determine their susceptibility to antibiotics in adults hospitalized and referred to the Vase’ee Hospital in Sabzevar between 2016 and 2017. Material and methods: This descriptive cross-sectional study was performed on 256 individuals hospitalized in or referred to the Vase’ee hospital sabzevar University of Medical Sciences in 2017. Identification of bacteria was performed using standard tests, and their susceptibility was determined by disk diffusion method. The data were analyzed using t-test, Chi-square and Fisher’s exact test with 95% confidence interval. Significance level was considered less than 0.05. Results: Of 256 patients, 59.7 % and 40.3% were female and male, respectively. The most frequently isolated pathogen were Escherichia coli(50.8%), Klebsiella(17.6%),Coagulase-Negative Staphylococci(8.7%), Enterobacter(7.8%), Staphylococcus saprophyticus(3.9%), Staphylococcus epidermidis(3.2%). E. coli as most common pathogen of urinary tract infections showed the most resistance to ampicillin and the least resistance to Imipenem indicated. In total, regardless of the type of bacteria, the highest resistance was against amoxicillin and the lowest resistance was against Imipenem. Discussion & Conclusion: According to the results of this study, in order to select the appropriate antibiotic for treatment of urinary tract infections, bacterial spectrum and antibiotic susceptibility of urinary pathogens should be considered. Key words: urinary tract infection, antibiotics, antibiotic resistance
| Item Type: | Thesis (Doctoral) |
|---|---|
| Uncontrolled Keywords: | urinary tract infection, antibiotics, antibiotic resistance |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine, Health and Life Sciences > School of Medicine |
| Depositing User: | Saeed Shoja |
| Date Deposited: | 09 May 2018 04:02 |
| Last Modified: | 12 Jan 2019 04:04 |
| URI: | http://eprints.medsab.ac.ir/id/eprint/350 |
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