Heteropolyacid-based ionic liquid [Simp] 3 PW 12 O 40 nanoparticle as a productive catalyst for the one-pot synthesis of 2H-indazolo[2,1- b ]phthalazine-triones under solvent-free conditions

Tayebee, Reza and Fattahi Abdizadeh, M. and Maleki, Behrooz and Shahri, Elham (2017) Heteropolyacid-based ionic liquid [Simp] 3 PW 12 O 40 nanoparticle as a productive catalyst for the one-pot synthesis of 2H-indazolo[2,1- b ]phthalazine-triones under solvent-free conditions. Journal of Molecular Liquids, 241. pp. 447-455. ISSN 01677322

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Abstract

A novel Keggin-type heteropolyacid-based ionic liquid [Simp]3PW12O40 was developed via the reaction of the as synthesized ionic liquid 3-sulfonic acid 1-imidazolopyridinium hydrogen sulfate [Simp]HSO4 with an aqueous solution of H3PW12O40. Then, the formulated [Simp]3PW12O40 was changed to the nano-form via solvothermal processing in tetralin at 220 °C. After that, the provided powdered solid nanomaterial was characterized by FT-IR, 1H NMR, XRD, SEM, EDX and TGA analyses. Then, the focused nanomaterial was handled as a productive and encouraging nanocatalyst for the establishment of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione attendants through one-pot, multi-component contraction of aldehydes, phthalhydrazide, and dimedone under solventless status and the generality and practical tolerance of this useful and environmentally benign method are illustrated. The simple work-up, smooth reaction conditions, good to excellent yields, and reasonably short reaction times are the particular benefits of this protocol. Besides, the new nano-powdered ionic liquid was a successful and modest catalyst that could definitely be recycled and reused several times without apparent decrease in its catalytic activity.

Item Type:	Article
Subjects:	R Medicine > R Medicine (General)
Depositing User:	Saeed Shoja
Date Deposited:	26 Feb 2018 06:45
Last Modified:	26 Feb 2018 06:45
URI:	http://eprints.medsab.ac.ir/id/eprint/203

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